Zandile (aka Zandi) Hlatshwayo was introduced to the music industry in 2003 when she met Themba Mkhize who gave her informal training. She then started working for him as a backup vocalist. He introduced her to people like Shaluza Max Mtambo and Lucas Senyatso, among many others. In 2005, she became the lead of a group called Amantombazane, which was produced by Sizwe Zako. In 2007, Hlatshwayo joined Wadz Music Company, where she released her first solo house album, Life is a Journey. In 2009, she became a member of Soweto Spiritual Singers, which is led by Vicky Vilakazi from Joyous Celebration, and they performed at the 2010 Soccer World Cup with R Kelly. Hlatshwayo has also performed with Lira, Bebe Winans, Sechaba Padi, Thabo Mdluli, Jo Nina, Uche, Patrick Duncan, and Moses Molelekwa’s jazz band, among others.